Determination of Emerging Contaminants in Surface Water Resources of EYDAP following wide-scope Target and Non-Target Screening

The aim of the study was to perform extended monitoring of emerging contaminants in the water samples from three reservoirs of drinking water of EYDAP, Evinos, Mornos and Marathonas. Solid-Phase Extraction (SPE) by mixed-mode sorbent was used during the sample preparation to ensure the extraction of compounds with a wide range of physicochemical properties and very low limits of detection. The extracts were analyzed by complimentary chromatographic techniques, including Reversed Phase (RP) and Hydrophilic Interaction Liquid Chromatography (HILIC) coupled to Quadrupole-Time-of-Flight Mass Spectrometry (QToF-MS) due to its increased selectivity. Wide-scope target screening was performed by in-house databases consisting of 3,000 compounds, including several classes of emerging contaminants, naturally occurring compounds and endogenous metabolites. For the suspect screening, a database of approximately 40,000 compounds (REACH chemicals, industrial chemicals, biocides, PPCPs, surfactants and compounds from the NORMAN network monitoring programs) was used. Non-target screening was also performed for the identification of unknown unknowns in the analyzed samples.